featured review & perspective articles (work led or co-led by our lab)

 

 


Shendure et al. Genomic Medicine-Progress, Pitfalls, and Promise. Cell (2019)
PMID: 30901547
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Klein et al. Identifying Novel Enhancer Elements with CRISPR-Based Screens. ACS Chemical Biology (2018)
PMID: 29300083
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Starita et al. Variant Interpretation: Functional Assays to the Rescue. AJHG (2017)
PMID: 28886340
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Shendure. Human genomics: A deep dive into genetic variation. Nature (2016)
PMID: 27535530
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Gasperini et al. The power of multiplexed functional analysis of genetic variants. Nature Protocols (2016)
PMID: 27583640
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Snyder et al. Haplotype-resolved genome sequencing: experimental methods and applications. Nature Reviews Genetics (2015)
PMID: 25948246
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Shendure & Akey. The origins, determinants, and consequences of human mutations. Science (2015)
PMID: 26404824
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Shendure. Life after genetics. Genome Medicine (2014)
PMID: 25473425
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Shendure. 2012 Curt Stern Award address. American Journal of Human Genetics (2013)
PMID: 23472756
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Snyder et al. Noninvasive fetal genome sequencing: a primer. Prenatal Diagnosis (2013)
PMID: 23553552
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Shendure & Lieberman-Aiden. The expanding scope of DNA sequencing. Nature Biotechnology (2012)
PMID: 23138308
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Shendure. Next-generation human genetics. Genome Biology (2011)
PMID: 21920048
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Bamshad et al. Exome sequencing as a tool for Mendelian disease gene discovery. Nature Reviews Genetics (2011)
PMID: 21946919
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Ng et al. Massively parallel sequencing and rare disease. Human Molecular Genetics (2010)
PMID: 20846941
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Turner et al. Methods for genomic partitioning. Annual Reviews in Genomics and Human Genetics (2009)
PMID: 19630561
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Shendure. The beginning of the end for microarrays? Nature Methods (2008)
PMID: 18587314
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Shendure et al. Advanced sequencing technologies: methods and goals. Nature Reviews Genetics (2004)
PMID: 15143316
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