featured review & perspective articles (work led or co-led by our lab)

Askary et al. The lives of cells, recorded. Nature Review Genetics (2024)
PMID: 39587306
PDF

Liao, Choi, Shendure. Molecular recording using DNA Typewriter. Nature Protocols (2024)
PMID: 38844553
PDF

Domcke, Shendure. A reference cell tree will serve science better than a reference cell atlas. Cell (2023)
PMID: 36931241
PDF

Nathans et al. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin. Methods and Techniques for Skin Research (2024)
PMID: 38643988
PDF

Boeckh et al. The Seattle Flu Study: when regulations hinder pandemic surveillance. Nature Medicine (2022)
PMID: 34937879
PDF

Gordon, Inoue, Martin, Schubach et al. lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Nature Protocols (2020)
PMID: 32641802
(with Ahituv and Kircher Labs)
PDF

Qiu, Shendure. A continuous model of early mammalian development. Nature (2021)
PMID: 33931776
PDF

Gasperini, Tome, Shendure. Towards a comprehensive catalogue of validated and target-linked human enhancers. Nature Reviews Genetics (2020)
PMID: 31988385
PDF

Shendure et al. Genomic Medicine-Progress, Pitfalls, and Promise. Cell (2019)
PMID: 30901547
PDF

Kim et al. Mechanisms of Interplay between Transcription Factors and the 3D Genome. Molecular Cell (2019)
PMID: 31521504
PDF

Klein et al. Identifying Novel Enhancer Elements with CRISPR-Based Screens. ACS Chemical Biology (2018)
PMID: 29300083
PDF

Starita et al. Variant Interpretation: Functional Assays to the Rescue. AJHG (2017)
PMID: 28886340
PDF

Shendure et al. DNA sequencing at 40: past, present and future. Nature (2017)
PMID: 29019985
PDF

Shendure. Human genomics: A deep dive into genetic variation. Nature (2016)
PMID: 27535530
PDF

Gasperini et al. The power of multiplexed functional analysis of genetic variants. Nature Protocols (2016)
PMID: 27583640
PDF

Fields, Shendure. Massively Parallel Genetics. Genetics (2016)
PMID: 27270695
PDF

Snyder et al. Haplotype-resolved genome sequencing: experimental methods and applications. Nature Reviews Genetics (2015)
PMID: 25948246
PDF

Shendure, Akey. The origins, determinants, and consequences of human mutations. Science (2015)
PMID: 26404824
PDF

Kircher, Shendure. Running spell-check to identify regulatory variants. Nature Genetics (2015)
PMID: 26220134
PDF

Shendure. Life after genetics. Genome Medicine (2014)
PMID: 25473425
PDF

Shendure. 2012 Curt Stern Award address. American Journal of Human Genetics (2013)
PMID: 23472756
PDF

Kumar et al. Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course. PLoS One (2014)
PMID: 25192356
PDF

Snyder et al. Noninvasive fetal genome sequencing: a primer. Prenatal Diagnosis (2013)
PMID: 23553552
PDF

Shendure, Lieberman-Aiden. The expanding scope of DNA sequencing. Nature Biotechnology (2012)
PMID: 23138308
PDF

Kohane, Shendure. What's a Genome Worth? Science Translational Medicine (2012)
PMID: 22572879
PDF

Shendure. Next-generation human genetics. Genome Biology (2011)
PMID: 21920048
PDF

Bamshad et al. Exome sequencing as a tool for Mendelian disease gene discovery. Nature Reviews Genetics (2011)
PMID: 21946919
PDF

Cooper, Shendure. Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nature Reviews Genetics (2011)
PMID: 21850043
PDF

Ng et al. Massively parallel sequencing and rare disease. Human Molecular Genetics (2010)
PMID: 20846941
PDF

Turner et al. Methods for genomic partitioning. Annual Reviews in Genomics and Human Genetics (2009)
PMID: 19630561
PDF

Mamanova et al. Target-enrichment strategies for next-generation sequencing. Nature Methods (2010)
PMID: 20111037
PDF

Shendure. The beginning of the end for microarrays? Nature Methods (2008)
PMID: 18587314
PDF

Shendure et al. Advanced sequencing technologies: methods and goals. Nature Reviews Genetics (2004)
PMID: 15143316
PDF

Shendure, Ji. Next generation DNA sequencing. Nature Biotechnology (2008)
PMID: 18846087
PDF