featured review & perspective articles (work led or co-led by our lab)
Liao, Choi, Shendure. Molecular recording using DNA Typewriter. Nature Protocols (2024)
PMID:
38844553
PDF
Domcke, Shendure. A reference cell tree will serve science better than a reference cell atlas. Cell (2023)
PMID:
36931241
PDF
Nathans et al. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin. Methods and Techniques for Skin Research (2024)
PMID:
38643988
PDF
Boeckh et al. The Seattle Flu Study: when regulations hinder pandemic surveillance. Nature Medicine (2022)
PMID:
34937879
PDF
Gordon, Inoue, Martin, Schubach et al. lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Nature Protocols (2020)
PMID:
32641802
(with Ahituv and Kircher Labs)
PDF
Qiu, Shendure. A continuous model of early mammalian development. Nature (2021)
PMID:
33931776
PDF
Gasperini, Tome, Shendure. Towards a comprehensive catalogue of validated and target-linked human enhancers. Nature Reviews Genetics (2020)
PMID:
31988385
PDF
Shendure et al. Genomic Medicine-Progress, Pitfalls, and Promise. Cell (2019)
PMID:
30901547
PDF
Kim et al. Mechanisms of Interplay between Transcription Factors and the 3D Genome. Molecular Cell (2019)
PMID:
31521504
PDF
Klein et al. Identifying Novel Enhancer Elements with CRISPR-Based Screens. ACS Chemical Biology (2018)
PMID:
29300083
PDF
Starita et al. Variant Interpretation: Functional Assays to the Rescue. AJHG (2017)
PMID:
28886340
PDF
Shendure et al. DNA sequencing at 40: past, present and future. Nature (2017)
PMID:
29019985
PDF
Shendure. Human genomics: A deep dive into genetic variation. Nature (2016)
PMID:
27535530
PDF
Gasperini et al. The power of multiplexed functional analysis of genetic variants. Nature Protocols (2016)
PMID:
27583640
PDF
Fields, Shendure. Massively Parallel Genetics. Genetics (2016)
PMID:
27270695
PDF
Snyder et al. Haplotype-resolved genome sequencing: experimental methods and applications. Nature Reviews Genetics (2015)
PMID:
25948246
PDF
Shendure, Akey. The origins, determinants, and consequences of human mutations. Science (2015)
PMID:
26404824
PDF
Kircher, Shendure. Running spell-check to identify regulatory variants. Nature Genetics (2015)
PMID:
26220134
PDF
Shendure. Life after genetics. Genome Medicine (2014)
PMID:
25473425
PDF
Shendure. 2012 Curt Stern Award address. American Journal of Human Genetics (2013)
PMID:
23472756
PDF
Kumar et al. Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course. PLoS One (2014)
PMID:
25192356
PDF
Snyder et al. Noninvasive fetal genome sequencing: a primer. Prenatal Diagnosis (2013)
PMID:
23553552
PDF
Shendure, Lieberman-Aiden. The expanding scope of DNA sequencing. Nature Biotechnology (2012)
PMID:
23138308
PDF
Kohane, Shendure. What's a Genome Worth? Science Translational Medicine (2012)
PMID:
22572879
PDF
Shendure. Next-generation human genetics. Genome Biology (2011)
PMID:
21920048
PDF
Bamshad et al. Exome sequencing as a tool for Mendelian disease gene discovery. Nature Reviews Genetics (2011)
PMID:
21946919
PDF
Cooper, Shendure. Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nature Reviews Genetics (2011)
PMID:
21850043
PDF
Ng et al. Massively parallel sequencing and rare disease. Human Molecular Genetics (2010)
PMID:
20846941
PDF
Turner et al. Methods for genomic partitioning. Annual Reviews in Genomics and Human Genetics (2009)
PMID:
19630561
PDF
Mamanova et al. Target-enrichment strategies for next-generation sequencing. Nature Methods (2010)
PMID:
20111037
PDF
Shendure. The beginning of the end for microarrays? Nature Methods (2008)
PMID:
18587314
PDF
Shendure et al. Advanced sequencing technologies: methods and goals. Nature Reviews Genetics (2004)
PMID:
15143316
PDF
Shendure, Ji. Next generation DNA sequencing. Nature Biotechnology (2008)
PMID:
18846087
PDF